Early brain tumor resection can effectively improve the patient’s survival rate. However, resection quality and safety can often be heavily affected by intra-operative brain tissue shift due to factors, such as gravity, drug administration, intracranial pressure change, and tissue removal. Such tissue shift can displace the surgical target and vital structures (e.g., blood vessels) shown in pre-operative images while these displacements may not be directly visible in the surgeon’s field of view.

Intra-operative ultrasound (iUS) is a robust and relatively inexpensive technique to track intra-operative tissue shift and surgical tools, but to help update pre-surgical plans with this information, accurate and robust image registration algorithms are needed to relate pre-surgical MRI to iUS images. Despite the great progress so far, medical image registration techniques still have not made into the surgical room to directly benefit the patients with brain tumors.

This challege/workshop will provide a snapshot of the current progress in the field through extended discussions and provide researchers an opportunity to characterize their image registration methods on newly released standardized datasets of iUS-guided brain tumor resection.

CuRIOUS 2018 is an official satellite event of MICCAI 2018.

Important dates

April, 1st Challenge website launched
April, 15th Registration opened
July, 10th
Registration closed (manuscript due)
July 21st Manuscript camera-ready due
August, 25th Test data released
September, 7th
Test data result due
September, 16th Challenge workshop at MICCAI'2018







To register for the challenge and receive data and notifications, please read the instructions in the "Join" tab.

As this is an official MICCAI satellite event, to be considered for prizes and publications, at least one person from the team must present their methods and results at the workshop on Sep 16, 2018. To receive the test data for the challange, the teams must submit the methodological manuscripts describing their algorithms and results on the training dataset by July 10, 2018, our new deadline. 

Upon challenge registration before July 10, 2018, the teams can still submit their method papers until Aug 20, 2018 in order to obtain the test data and participate the final contest. Although their manuscripts won't be included in the post-conference proceedings, their results will be included in the final journal article that summarizes the challenge.

The methodologies of all the official participants have been published in the following book:

Simulation, Image Processing, and Ultrasound Systems for Assisted Diagnosis and Navigation, International Workshops, POCUS 2018, BIVPCS 2018, CuRIOUS 2018, and CPM 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 16–20, 2018, Proceedings

Editors: Stoyanov, D., Taylor, Z., Aylward, S., Tavares, J.M.R.S., Xiao, Y., Simpson, A., Martel, A., Maier-Hein, L., Li, S., Rivaz, H., Reinertsen, I., Chabanas, M., Farahani, K. (Eds.)

The summary for the 2018 Challenge:

Y. Xiao,Hassan Rivaz, Matthieu Chabanas, M. Fortin, I. Machado, Y. Ou, M.P. Heinrich, J.A. Schnabel, X. Zhong, A. Maier, W. Wein, R. Shams, S. Kadoury, D. Drobny, M. Modat, I. Reinertsen, “Evaluation of MRI to ultrasound registration methods for brain shift correction: The CuRIOUS2018 Challenge,” arXiv:1904.10535.

Keynote Speaker

Ole Solheim, MD, PhD

Dr. Ole Solheim is a consultant neurosurgeon at St.Olavs University Hospital and Professor at the Norwegian University of Science and Technology (NTNU), Trondheim, Norway. He has extensive experience with intraoperative ultrasound both in terms of clinical use and research, and he has been involved in research and development of new technology for neurosurgery for more than a decade. His main area of research interest is brain cancer including risk factors, tumor growth, quality of life, imaging and treatment strategies.



This challenge is co-sponsored by: